Diagnostic value of cutaneous findings in adult Still disease, a rare autoinflammatory disease

RS Bumbacea, L Vasile, LG Popa, I Tudose, C Giurcaneanu

Abstract



Adult onset Still disease (AOSD) is a rare autoinflammatory syndrome of unknown etiology, characterized by fever, arthralgia or arthritis, evanescent rash and systemic involvement. AOSD has variable clinical pictures, from mild symptoms to life-threatening complications, and variable disease course (self-limited, intermittent or chronic). The heterogeneous clinical presentation often makes the diagnosis difficult for an inexperienced clinician. Therefore, cutaneous manifestations are considered important clues for correct diagnosis. Besides the typical salmon-pink, macular or maculo-papular rash, which represents one of the major diagnosis criteria, AOSD can be associated with various types of skin lesions (e.g. persistent, erythematous, slightly scaly or crusted papules with linear configuration) with characteristic histological features. In this short review, we present a series of important diagnostic aspects in AOSD, insisting on cutaneous manifestations, according to available literature data. 


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Copyright (c) 2014 Romanian Journal of Clinical and Experimental Dermatology

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—Print : ISSN 2392–7461, ISSN-L 2392–7461 
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